After topping their group ahead of traditional European giants and neighbours England, The Dragons have now roared into the semi-final of the Euro 2016, beating Belgium 3-1 last night (July 1).
While all eyes will be on Bale during Wednesday's clash in Lyon, Wales's other big name, Aaron Ramsey, will miss out after picking up a second booking of the tournament in the last-eight.
"It's Portugal versus Wales, nothing more", said Bale when asked about coming up against Ronaldo at the Parc Olympique Lyonnais.
"Of course the players have a bad taste left in their mouth but ultimately you have the match and things didn't go our way".
German World Cup victor Lothar Matthaus messaged: "Wow!" That's another objective, so we'll think about that, about qualification, then there's a Euro in 2020. As a back three or as a team we will look to overcome that challenge.
His team "defended like soldiers" and played smartly, taking the game to Belgium after initially looking flustered.
"But for us it's just about Wales again, as it has been the whole time". We knew that they had plenty of talent and very good individuals, but we have shown what a real team can do.
Arsenal midfielder Ramsey's performances throughout Euro 2016 have proven there is more to Chris Coleman's side that Gareth Bale, with the 25-year-old enjoying his best run of form since late 2013.
"We had a young average age".
Belgium coach Marc Wilmots will face hard questions about his failure to achieve more with one of his nation's finest collections of footballers, who also fell in the last eight at the 2014 World Cup.
Red Devils goalkeeper Thibaut Courtois declined to back Wilmots, and Hazard says his boss has a decision to make.
Wilmots will now naturally come under pressure for failing to meet expectations given the quality that he had in his squad, and he didn't receive any great reassurances from Courtois in terms of wishes for him to stay on in his current position.
Wales have him tied down for another two years and he'll want to lead his country to Russian Federation in 2018, but right now his stock has never been higher. "We have a great team spirit".
"Today we have had a disappointment, but I think he will have a think, he will decide later if he wants to continue with us and if not, then we will wish him luck for the future".