In their first telephone conversation, Kerry offered his congratulations to newly appointed Johnson in the top British diplomatic post.
But fate seems to have had other plans for the former London mayor.
Quick to open its market, William Hill has made Boris Johnson a 6/4 market favourite to be the "first minister to quit Theresa's Gang of Four".
The French foreign minister Jean-Marc Ayrault earlier accused his new counterpart of lying, saying: "He lied a lot to the British people and now it is him who has his back against the wall".
The ever-quirky and always entertaining former London mayor, well-known for his antics and often embarrassing public stunts was heckled by a bereft crowd of officials and guests.
In an op-ed published in April, he claimed President Obama removed a bust of Winston Churchill from the Oval Office upon assuming the presidency in 2009 because "it was a symbol of the part-Kenyan president's ancestral dislike of the British empire-of which Churchill had been such a fervent defender", comments several leading British members of Parliament (rightly) condemned as racist.
Now resurrected as the foreign secretary, Johnson's appointment has been predictably received with much mirth and moans in European capitals and elsewhere.
But Johnson's charm operation earned a mixed reception from a party guestlist stuffed with business chiefs, diplomats, actors and writers who closely followed his campaign for Britain to quit the European Union in the June 23rd referendum.
President Barack Obama has called new British Prime Minister Theresa May to congratulate her. The single most telling reaction from the West has to be that of U.S. State Department spokesman Mark Toner, who, upon learning the news during a press conference, broke into a broad, Cheshire Cat grin before snapping back to a blank poker face with preternatural quickness and delivering an anodyne answer. During the referendum, he drew a parallel between European Union politicians with ambitions to unite Europe and Adolf Hitler. He says Obama is confident the USA will keep working to strengthen relations "irrespective of specific personalities".
In her first speech as prime minister outside 10 Downing Street on Wednesday, May said: "We will make Britain a country that works not for a privileged few, but for every one of us".
Speaking outside the foreign office, he said he wanted to reshape "Britain's global profile and identity as a great global player".
May won the leadership battle and quickly sacked Gove, who is now seen as treacherous by many Conservatives. "However, the composition of the new Cabinet shows that the focus is less on the future of the country, but more about satisfying the internal cohesion of the Tory Party".
I need a partner with whom I can negotiate and who is clear, credible and reliable.
In the Daily Telegraph, May's appointments and her vision of One Nation Conservatism were welcomed and her appointment of Leave campaigners described as "the best possible way of uniting not just her Government, but the country at large".
Despite a litany of gaffes and insulting slurs against everyone from Liverpudlians to the people of Papua New Guinea, Boris will be Britain's representative to the world.