Kerber beat five-time Wimbledon champ Venus Williams 6-4, 6-4 on Thursday to advance to her second major final, and the 2016 Wimbledon title match will be the first time that two players will meet in two different major finals in the same year since Amelie Mauresmo beat Justine Henin in the Australian Open and Wimbledon finals in 2006.
It took Serena Williams just 49 minutes to win her Wimbledon semifinal on Thursday, emphatically cruising by 50th-ranked Elena Vesnina, 6-2, 6-0.
But at the end of the day, we don't think Serena will lose three straight Grand Slam finals, especially at one of her favourite places on the planet: Wimbledon Centre Court. She won 28 of her 31 points on serve for the match, and lost just one point on her first serve.
She will look for a seventh Wimbledon title and a record-equalling 22nd Grand Slam win and the 34-year-old admitted she was elated to progress. "We've had a lot of tough matches before and on this surface I knew she could bring it today", said Serena, who will be playing her ninth Wimbledon final.
"If you're going to cry and be insane after every loss, I think your nerves will be dead by the end of your career", she said.
Serena Williams says she is determined to make up for 2016 grand slam disappointment after reaching the Wimbledon final easily on Thursday. "Everything worked and it is a very good feeling", said Kerber, who has lost five of seven matches against Serena.
That means Venus still has a chance to leave Wimbledon with a trophy, just like her sister.
Serena thrashes Vesnina to reach Wimbledon final
"I made a lot of errors", Williams said when asked how she planned to turn things around.
The stakes have rarely been higher for Williams, who, at nearly 35, will unlikely get many more chances to equal Steffi Graf's open-era benchmark tally of major titles. "This makes me much more risky than on hard".
Angelique Kerber takes first blood against Venus Williams in the first set, as the pair goes on to split the first four games for a 2-2 tie. When I go into a final, I, too, need to be fearless like she was.
The Williams sisters beat Vesnina and fellow Russian Ekaterina Makarova 7-6 (7-1) 4-6 6-2 to reach the semi-finals.
Adamant that Graf's Open-era record of 22 singles majors was never her goal, Williams refuses to discuss a number she has failed to equal - when heavily favoured to - three times.
Left-handed Kerber had the upper hand in the baseline exchanges against eighth-seeded Venus throughout a topsy-turvy first set. "I'm enjoying my tennis, I am playing the best tennis of my life and enjoying myself".
"She's going to win this one", he said.