The leg-spinner has always been seen as the future of England's spin options but the resurgence of Moeen Ali, man of the series against South Africa, means his Test debut may be further away than first thought.
The Durham opener only averaged 15.87 in eight innings during England's 3-1 series win over his native South Africa, which concluded with a 177-run victory in the fourth Test at Old Trafford on Monday.
"I've had 10 years as a professional so I'd hope I have worked things out by now".
National selector James Whitaker said: "Chris Woakes has proved his fitness and returns to the squad having missed most of the summer through injury".
"I am sure he will find his confidence and look to score runs in the remaining matches of this season", added Whitaker.
Last winter Crane was plucked from grade cricket by New South Wales to become the first overseas player to play for them in the Sheffield Shield since Imran Khan in 1984-85. "He would have known that and been disappointed", Stokes, his teammate at Durham, told Sky Sports.
I don't envy him starting with a day-night Test - West Indies, I think, will be less powerful then South Africa, but the ball will nip around under the lights.
Skipper Joe Root said new leg spinner Mason Crane was typical of the modern cricketer who feels at ease in switching between the many formats of the game.
Tom Westley, number 679, retains his place in the squad while Chris Woakes returns to the squad and could displace the unfortunate Toby Roland-Jones, who has impressed in his brief opportunity as an global seamer.
The 20-year-old has endured an indifferent season with Hampshire but will get his chance to stake a claim for an Ashes spot after making a positive impression in England's Twenty20 series against the Proteas in June.
SURREY'S Mark Stoneman will become Alastair Cook's latest opening partner when England take on West Indies next week.
The opening Test in Birmingham will be the first-ever day-night Test to be staged in the country.
I suspect Mason Crane won't play at Edgbaston - it's a match where England will get their seamers out as the pink ball could do all sorts of odd things - but we will see him later in the series.
Alastair Cook (Essex), Mark Stoneman (Surrey), Tom Westley (Essex), Joe Root (Yorkshire, capt), Dawid Malan (Middlesex), Ben Stokes (Durham), Jonathan Bairstow (Yorkshire, wk), Moeen Ali (Worcestershire), Chris Woakes (Warwickshire), Toby Roland-Jones (Middlesex), Stuart Broad (Nottinghamshire), Mason Crane (Hampshire), James Anderson (Lancashire).