Suarez's smart step over then caught Iraizoz cold again for Barcelona's second, with Aleix Vidal also producing a tidy backheel in the build-up.
Aleix Vidal was handed his first start of the season, as he started in the alongside Messi and Suarez.
For a week previous it had been Catalan independence.
Girona were facing Barcelona for the first time in the top flight and their tight little Montilivi Stadium recorded its highest ever attendance.
That the match fell at the end of a week in which tensions had risen over Catalonia's desire to hold a referendum over independence added to the unique atmosphere.
"We are trying to be together in both attack and defence".
The Uruguayan sealed a comfortable 3-0 win over Catalan rivals Girona with a clinical finish to reach a remarkable tally of 87 goals in his century of league games. "He's the best player in the world and if you don't stick to him, he can score at any moment", Maffeo said. "He is too good".
However, the Blaugrana still emerged triumphant, with Luis Suarez's strike and own goals from Francisco Aday and Gorka Iraizoz giving the visitors their sixth consecutive league win of the new season.
One of the most intriguing events of the game was Maffeo man marking Messi, a very specific task proven by the fact that Maffeo made only 5 passes in the 77 minutes he was on the pitch. We tried to get the better of them by playing in the space and taking advantage of Leo's movement.
No longer Lionel Messi + 10 more, each and every player is making a contribution, and undoubtedly Ernesto Valverde has to take the credit for instilling such a mentality amongst his squad, including the senior players, quickly. "Honestly Maffeo, the game is over".