The Cavaliers (29-19) lost the road game 125-114 to extend their recent struggles, which include a much-publicised team meeting where Love was a target for the group's frustration. He will not return to the game and his status moving forward remains unclear.
According to a news release, the injury is a non-displaced fracture of the fifth metacarpal.
Love dealt with a broken right hand as a member of the Minnesota Timberwolves in 2009.
In 2017, he underwent knee surgery five days before the All-Star Game.
Last season, Love underwent minor knee surgery on February 14, causing him to miss the All-Star Game five days later. So unfortunately for Love, he might miss back to back All-Star games.