The annual gathering is scheduled for January 23-26, with the theme Creating A Shared Future In A Fractured World.
Last year's conference came the same week of Trump's inauguration and delegates at the time predicted Trump would prove a more pragmatic leader than he suggested on the campaign trail or on Twitter.
But White House press secretary Sarah Huckabee Sanders said Mr Trump would be promoting his policies for strengthening American businesses, industries and workers.
Sitting presidents have rarely attended the event, held at a ski resort in the Swiss mountains, fearing its reputation for elitism may not play well politically at home. Yet a White House statement indicated Trump would not hesitate to bring his nationalist message to the assemblage of globalists.
Xi Jinping became the first Chinese president to attend the forum in 2017, when Mr Trump was represented by Anthony Scaramucci, who later served a brief and explosive tenure as Mr Trump's White House communications director.
Sanders later told reporters "the main reason he is going there" is to "talk about the America First agenda".
In his first year in office, Mr. Trump worked to reverse or rework America's relationship with trading partners, moves he argued would boost US economic interests.
The first sitting United States president to appear in the Swiss resort was Bill Clinton in 2000, at the forum's 30th-anniversary session. Presidents George H.W. Bush, George W. Bush and Barack Obama never attended the meeting.