The tie will be played over the weekend of March 17/18.
The two sides will meet at Liberty Stadium for a replay match.
Fabian Delph, David Silva and Leroy Sane all returned to action in the midweek Champions League win at Basel and Gabriel Jesus is also back in training.
In the FA Cup quarterfinal draws, all the big clubs will avoid each other- surprising no one!
The final is on Saturday, May 19 at Wembley.
The League One side host Mauricio Pochettino's men on Sunday, kick-off at 4pm.
The FA Cup, the worlds most famous domestic football Cup competition, has reached the fifth round stage - with 16 teams remaining and all harbouring hopes of lifting the famous trophy.
Jose Mourinho will be keen to try and steer his side to FA Cup glory this season after the Red Devils won both the League Cup and Europa League last term. "They think about the final next Monday".
Speaking to BBC Sport, Lawrenson said: "I was at this game when Huddersfield beat them in the league".