Mesut Ozil is likely to start (Picture: Getty Images)What are the odds?
So it looks like a 4-4-2 from the Frenchman, with Ozil and Mkhitaryan on either side of Lacazette.
Ramsey opened the scoring with a sidefooted finish on nine minutes but his second strike - an instinctive volleyed flick - was especially noteworthy.
Against the run of play, Aleksandr Golovin levelled in the 15th minute with a dipping, curling free-kick that flew into the top corner beyond the dive of goalkeeper Petr Cech.
While CSKA were unable to cope with Arsenal's speed of thought and movement at the back, they exposed the Gunners' own defensive weaknesses.
The North Londoners' dominance was then underlined ten minutes from the break as Ozil again provided the pass into the danger area, and after Vasily Berezutskiy failed to clear his lines, the prowling Lacazette composed himself and rifled his effort low into the net from 18 yards.
Liverpool fans have thanked Arsenal following a stunning performance by Alex Oxlade-Chamberlain in the Champions League quarter final against Manchester City on Wednesday.
Ozil was again the creator when Lacazette also grabbed a double by shooting into the far corner for his first goal from open play in almost three months.
However, the second leg should still be a mere formality to maintain their hopes that an otherwise dispiriting season can have a happy ending.
The task of picking up a positive home result in the opening leg will not be helped if the number of stay-away supporters remains the same.
Germany's Leipzig, playing in European competition for the first time, put themselves in a good position to progress after a Timo Werner goal on the stroke of halftime sank Marseille.