The Team Sky rider suffered cuts in the crash ahead of the time trial in Jerusalem, with his right knee looking particularly grazed.
All eyes are on Froome as he bids to pull off a Grand Tour treble with a UCI investigation still ongoing regarding the adverse analytical finding he returned during his Vuelta a Espana triumph past year.
Team Sky told Cyclingnews that Froome is "fine" and "there is no significant damage or cause for concern".
The Giro gets underway later on Friday in the Israeli city. "To have the win and time on the other GC guys is a pefect start for me and the team." said Dumoulin.
With so much talk about his adverse test for asthma drug salbutamol at last year's Vuelta and whether he should even be here, the start of the race was meant to bring some respite.
The victor of the start-up phase and the first holder of the pink shirts was the defending champion of the race, the Dutchman Tom Dumoulin - captain "Sunweb" just two seconds ahead of Australian Roanne Dennis and became a three-time victor of the Giro stages.
He is the first rider since Paolo Savoldelli (2005-06) to win a Giro and start the following one by immediately taking the maglia rosa.