Hulu's A Handmaid's Tale - which won the award for best drama series previous year - earned 20 nods.
"Game of Thrones", which sat out the awards a year ago because it missed the eligibility window, received 22 nominations, the most of any series.
The return of "Thrones" did tighten the race up on the drama side, but the absence of "Veep" from contention this year didn't seem to do much to help on the comedy side.
And during Thursday's 2018 Emmy nominations announcement, it was revealed that it's been nominated for 22 more, including Best Drama Series, Best Directing for a Drama Series and Best Writing for a Drama Series.
HBO's Game of Thrones is closely followed by dystopian sci-fi series The Handmaid's Tale, which gained 20 nominations and won top drama previous year.
"Saturday Night Live, " riding high in the ratings with its relentless pillorying of the Trump administration, was rewarded with 21 nods.
The short-lived revival of "Roseanne", canceled because of star Roseanne Barr's racist tweet in May, drew only one major nomination: a supporting actress nod for Laurie Metcalf. "We are pleased to have these two talented performers join us to announce this year's Emmy nominees and to celebrate television excellence".
Other best drama contenders include "The Crown", NBC's family drama "This Is Us", Cold War spy series "The Americans" on FX (FOXA.O) and "Westworld".
Lead actress in a drama series: Claire Foy (The Crown); Tatiana Maslany (Orphan Black); Elisabeth Moss (The Handmaid's Tale); Sandra Oh (Killing Eve); Keri Russell (The Americans) and Evan Rachel Wood (Westworld).