"It's up to him to be aware of all the demands of high level football, and I do not think he is fully aware of it".
British media reports have said Valencia has fallen out with Portuguese Mourinho who is under heavy criticism after the club's worst start to a season since 1989-90. "I expect the same", said Giggs.
The 43-year-old former England worldwide has been a stern critic of Mourinho, who in turn has hit back at the one-time United stalwart.
The Red Devils were also dumped out of the League Cup by Derby County last week - and they failed to win again when they were held to a goalless draw by Valencia at Old Trafford on Tuesday night. "I would prefer to say that last season we finished second in the league, were runners-up in the FA Cup and topped our Champions League group".
"I am not interested in that, I don't need to know what Paul Scholes said", Mourinho said.
United already sit five points off the top four after seven games and have daunting trips to Chelsea and Manchester City to come in two of their next five Premier League games as well as two Champions League clashes with Juventus. "On your bad days you roll your sleeves up, fight for the jersey and don't get distracted by the balloons out there".
The club's highest paid player, Alexis Sanchez, lost the ball a staggering 26 times in the mid-week stalemate with Valencia, and Keane eluded to the fact that fallouts and disagreements shouldn't hinder the efforts on matchdays.
Keane then added: "I'm not talking about Pogba". "We tried everything, but we were informed that the police had refused to give us an escort to the game so we were late".
"GMP has previously used police vehicles to accompany a team's coach but after a review of our core policing responsibilities it was decided that we would no longer provide this service at every fixture".