The 25-year-old singer debuted the song during an appearance on The Ellen DeGeneres Show, which is airing on Wednesday (November 7).
Grande chose to channel the classic musical number from "The First Wives Club", wearing bridal white alongside her two backup singers to resemble the film's stars Bette Midler, Goldie Hawn and Dianne Keaton.
After fans picked up on the lyrics in "thank u, next" directly referencing her former boyfriends including Mac Miller and Pete Davidson, Ariana revealed that she'd actually sent it to her exes days before she released it.
At one point, Grande stood up on a chair, bopping to her song in white heeled boots, but when she stepped down, she stumbled and fell, exclaiming, "Oh my god!" "Not long after, she laughed as she sang, "'Cause her name is Ari / And I'm so good with that". It's one thing to sing the words, "I'm so fucking grateful for my ex", and it's another to really look like you mean them.
Adding fuel to the fire, the biography of Zandhr on Spotify appears in the upside down font which Ariana Grande has used on her most recent album campaign.
But, just as the song says, Grande knows how to handle the pain.
Though the Ellen performance mostly goes off without a hitch, Grande and her companions mistakenly dance through the Ellen audience toward the studio exit when the song concludes. Throughout the rest of the performance, she keeps fighting back giggles. Oh my bad, I thought we were supposed to exit at the top. DeGeneres responds: "It's totally fine, we're happy that you came back".