Republicans, meanwhile, picked up at least three Senate seats in Missouri, North Dakota and in, and were poised to win a fourth in Florida. Democratic Senator Sherrod Brown was projected to hold his seat in Ohio.
But the return to split control of Congress after four years of GOP majorities will be a major test for the president, who has shown little ability to reach across the aisle.
Breaking the super majority in just one chamber would change the power dynamic in Raleigh.
"With Democrats' leadership in the state solidified, NY can pass policies previously blocked by Republicans to expand health care coverage, address climate change, and ensure women retain the right to make their own medical decisions", Jessica Post, executive director for the Democratic Legislative Campaign Committee, said in a statement on Tuesday. "When you talk locally, they're talking about protecting health care, they're talking about gun rights, gun reform", Wolf said.
In Indiana, Trump-backed businessman Mike Braun defeated Democratic incumbent Joe Donnelly.
Trump on Monday admitted the GOP could lose control of the House.
"That's what America wants to see". "We have to pass this bill", Biaggi said after her primary win about legislation that would codify Roe v. Wade. "And they want me to represent them and continue to serve them". "They are not going to put their money where their mouths are because they know there's nothing there", he told RT.
"I have worked at this poll the last three elections and this is the biggest turnout ever", said Bev Heidgerken, 67, a volunteer at a polling place in Davenport, Iowa.
Republicans - Trump's party - now have the majority in both chambers.
Anxious Republicans privately expressed confidence in their narrow Senate majority but feared the House was slipping away.
Trump's racially tinged anti-immigrant rhetoric, while unpopular among college-educated urban and suburban voters, seemed helpful in deeply conservative areas. Heidi Heitkamp of North Dakota and Missouri's Claire McCaskill appeared to be facing defeat.
Meanwhile, Sen. Joe Manchin III, the only Democrat to back Justice Kavanaugh, survived in West Virginia.
The Texas Senate election has turned out to be one of the most interesting in the 2018 midterms, with Democrat Beto O'Rourke mounting a serious challenge against Republican incumbent Ted Cruz.
"Republicans create jobs. Democrats create mobs", Republican National Committee chair Ronna Romney McDaniel tweeted. "We faced the toughest map in 60 years - and we didn't give up or back down". Democrats have campaigned heavily on the topic - attacking Republican attempts a year ago to repeal Obamacare health insurance reforms. About 15 percent said that this was the first time they'd voted in a midterm, according to CNN, compared to about 10 percent who said they were first-time voters in the 2016 election.
Sen. Bob Menendez of New Jersey beat Republican challenger Bob Hugin to win a third term.
Republicans hadn't publicly given up hope Tuesday though that they could pull off a victory, and continued making their push to voters.
Preliminary exit poll data found that Trump was a factor for nearly two-thirds of House voters.
That was enough for Karim Elmalki, voting in Sterling, Virginia. The president urged supporters to "pretend" he was on the ballot.
"This is basically, we are judging the Republican Party for the last two years". I don't care what they say.
"Barbara Comstock is good, but I don't like Trump", she said. He's like a shooter.
Republicans entered the night commanding the Senate only narrowly, 51-49.
In all it makes for a muddled picture that as much reflects regional identities, demographic differences and specific candidate strengths as it does Mr Trump's political power.
Over at Isaac Hunter's, Calabria said he was thankful Wake County voters appreciated "the forward-thinking" leadership the commission has been able to provide in recent years. If that's what voters are thinking about, it's an indication that Democrats accurately had the pulse of the electorate.
Trump has framed the elections as a choice between law and order maintained by Republicans and an out-of-control Democratic mob, while focusing heavily on hardline immigration campaign promises, including a legally dubious pledge to end birthright citizenship for the children of undocumented immigrants born in the US.