It was a buzzkill ending to what had been an entertaining fight in which Fury used constant movement and sharp punching to win rounds, while Wilder waited patiently to land the big punch.
Wilder thought he had done enough to win the fight.
The judges scored the bout 115-111 for Wilder, 114-112 for Fury and 113-113.
Deontay Wilder retained his WBC heavyweight crown here yesterday after battling to a split decision draw against Britain's Tyson Fury in a pulsating 12-round battle.
Neither man was overly upset by the verdict after a compelling bout in front of a frenzied Hollywood crowd. "The world knows I won the fight", said Fury, in the immediate aftermath of his effort.
Wilder, who also had Fury on the deck in the ninth round, was adamant he had won.
"It was what it was", Fury said.
"This has been a great night for the sport, for heavyweight boxing, and heavyweight boxing in the U.S.", said Costello. The Alabama native crashed a right hand just above Fury's ear in the eighth, sending him to the canvas. It doesn't matter to me where we do it.
Fury appeared to be on his way to a decision victory when he came out for the final round - and a minute later, he looked totally finished when Wilder put him on his back with a right-left combination. He was already heading to the canvas from Wilder's powerful right hand, but on the way down, Wilder connected with an even more vicious left hook. I don't know anyone on the planet that can move like that.
"Bless Wilder, thank you for the opportunity D. God bless you, and god bless America". "We defended a little better than in the last match, of course".
Staples Center had a frenzied atmosphere after the high-energy introductions, but the fighters settled into a technical bout early.
The champion began to fall short with jabs, and watched Fury comfortably take a left uppercut as he pursued the knockout while his left eye began to swell.
Fury struggled to generate consistent offence until a strong sixth round, likely costing himself early rounds. But more importantly, the Brit avoided the vaunted right hand of Wilder throughout and he made him pay for it repeatedly.
According to CompuBox punch statistics, Wilder landed 71 of 430 shots (17 percent), and Fury landed 84 of 327 (26 percent).
The punch wasn't the biggest of the fight, but Fury was stunned - and he responded by getting up and raising his aggression in an exciting round.
There were plenty more backing Fury on social media. Although he didn't land it with full force, he dropped Fury, who did not seem badly hurt. Everyone from Chadwick Boseman, Zlatan Ibrahimovic and Shaquille O'Neal to boxing stars Gennady Golovkin and Mikey Garcia gathered for the marquee heavyweight bout.