The Ryan Coogler-directed film has become the first superhero movie to be nominated for best picture in the drama category at the Golden Globes.
Marvel has made a heroic push for the film in recent months by hiring Oscar strategist Cynthia Swartz to lead the campaign for awards season with the support of Marvel President Kevin Feige and a "significant awards season budget".
For animated films, The Incredibles was nominated for Best Motion Picture - Musical Or Comedy in 2005 but lost to Sideways.
She will face off against The Handmaid's Tale's Elisabeth Moss, whose co-star in the hit Hulu series, Yvonne Strahovski, is nominated for best supporting actress. Samberg, meanwhile, is a two-time Golden Globe victor for his work on Brooklyn Nine-Nine, taking home statuettes in both the acting and producing categories.
For even the often-quirky selections of the Hollywood Foreign Press Association, a collection of 88 mostly less-known freelance film journalists, the strong support for Vice (which arrives in theatres on December 25) was a surprise.
Samberg and Oh did a test run as co-presenters at the Primetime Emmy Awards in September, which aired on NBC. Oh is also co-hosting the Golden Globes - with Andy Samberg of "Brooklyn Nine-Nine" - so you can safely predict how that category is going to go.
Every awards show provokes controversy in some manner, whether it happens with nominations, or the actual awards ceremony, or both.
It also earned nominations for Amy Adams' Lynne Cheney, Sam Rockwell's George W Bush and both the screenplay and direction by McKay, the veteran comedy filmmaker who once skewered politicians as a Saturday Night Live writer.
The Golden Globe Awards, like many shows of its kind, is caught up in a downward spiral of viewer indifference.
The Golden Globes will be held in Beverly Hills on January 6.
TNT received surprise nominations for the boring "The Alienist" - for limited series and for its star, the German actor Daniel Brühl.