May sought to strike a conciliatory tone, telling MPs they had the right to challenge her leadership and promising to hold more talks to salvage a workable deal by the rapidly approaching March 29 Brexit deadline.
Barnier regretted Westminster's massive rejection of the deal he negotiated with the government of British Prime Minister Theresa May and said that any future deal would still have to include approving the withdrawal agreement.
"The prime minister will then not necessarily be looking for brand new ideas that no one has thought of before, but actually seeking a consensus, actually a fresh initiative to find a solution that is negotiable with the European Union and that would command a majority in the House of Commons", Leadsom said. That's because on March 29, 2017, May delivered a notification to the EU Council President, Donald Tusk, under article 50 of the EU's Lisbon Treaty. Still, Tuesday's vote could ultimately mean that Britain might back down and not leave the E.U.at all after a second referendum.
Al Jazeera's Paul Brennan, reporting from London, said Brexit was "raising a question over the whole principle of parliamentary democracy" in Britain.
And a group of Conservative party rebels, led by three former ministers, have published a draft bill that, if passed, would compel the government to request a delay on Brexit to December while parliament dictates a new withdrawal plan.
May says cancelling Brexit is likelier than leaving with no deal, but she has repeatedly stressed her determination to leave and described any failure to carry out the mandate of the 2016 referendum as "catastrophic" for democracy.
The EU's chief negotiator Michel Barnier has told the European Parliament that the risk of no deal on Brexit has never been higher, and that he fears "more than ever" a chaotic United Kingdom departure from the bloc. The agreement gave Britain and the European Union until 2022 to reach a new permanent trade deal and stated the "backstop" would come into effect only if they failed to do so.
Ms May now faces a no confidence vote on called by the opposition Labour Party. Many members have been waiting months for the chance to vote on Brexit. If there is an impasse we will keep the option of another public vote.
May's political rival Boris Johnson told the BBC that her deal was "dead".
Here is how the country's papers view the historic moment in British politics.
"Every business will feel no deal is hurtling closer".
A loss by over 100 votes will put more pressure on May to consider her position.
European Union leaders were pleading Wednesday with the U.K.to finally get its act together on Brexit, end internal strife and come up with a realistic plan to leave the bloc - well over two years after Britain chose to leave the EU and departure just 10 weeks away. She still has plans to pursue an orderly Brexit.
Hardline Brexiteers and Remainers oppose the agreement for different reasons and many fear it could lock Britain into an unfavourable trading relationship with the EU.
If she wins Wednesday's confidence vote she will meet the leaders of the opposition parties in a "constructive spirit" to discuss the way forward, May said.
Constant commentary on Brexit has generated much ennui among the public on both sides of the divide; the 2016 referendum result was close: 51.9 per cent voted to leave the European Union and 48.1 per cent to stay in the EU.
If the deal fails to pass, May will only have until January 21 to present parliament with a "Plan B" for Brexit.