It seems, therefore, that Washington's next move will depend on how Maduro treats Guaido, and how Moscow responds to it.
Cody Weddle, an American journalist who has spoken with CBC News many times from Venezuela over the past several weeks and was deported this week after being detained for several hours by authorities, says the Maduro government accused him of treason, espionage and removing military artifacts.
He threatened to call for an outside military intervention "when the time comes", pointing to the constitution, which authorizes "the use of a Venezuelan military mission overseas, or foreigners inside the country".
"Intervention, intervention!" cried his supporters.
The 35-year-old Guaido, the head of Venezuela's National Assembly, earlier told thousands of supporters that he would soon embark on a nationwide listening tour before leading a march on the capital. "I still don't have power and I lost part of my food", she said, referring to food that spoiled due to the blackout.
Opposition leader Juan Guaido has called for people to take to the streets as has Maduro. We want to keep our journalism open and accessible and be able to keep providing you with news and analysis from the frontlines of Israel, the Middle East and the Jewish World.
Guaido took to Twitter to blast Maduro for the outage.
Maduro says one of Venezuelan energy facilities suffered cyberattack on Saturday
The western regions of Barinas, Tachira and Zulia remained without electricity while in other states the supply was proving unstable. Its cause is still unknown.
Emilse Arellano said urgent dialysis for her child had to be canceled Friday, after a night where staff worked in the light of cell phones.
While electricity returned to some parts of Caracas almost 24 hours after lights, phones and the internet stopped working, the blackout was another harsh blow to a country paralyzed by economic and political turmoil. We don't know when we're going to lose power again, or how we're going to deal with that.
"Sabotage is stealing Venezuelans" money, sabotage is burning food and medicine, sabotage is robbing elections", he wrote Friday using the hashtag #SinLuz, which translates to "without light'.
Netblocks, a Europe-based, non-government group based which monitors internet censorship, said online connectivity data indicates the outage is the largest in recent record in Latin America.
Thousands of homes in Caracas - a crime-ridden city of 2 million people - were without water.
"Today we'll show them in the streets", he said. USAID Administrator Mark Green, said, "Massive blackouts in Venezuela, anther tragic reminder of how Maduro has destroyed the power grid and energy sector", adding "Venezuelans deserve better".
Critics blame the government for failing to maintain the power grid.
The electricity disruption hit Venezuela on Thursday, with national electricity supplier Corpoelec alleging a "sabotage" at the Guri hydroelectric power plant. It gave no details.