Dr. John, whose given name was Malcolm John Rebennack Jr. and who was also called Mac, was born in New Orleans, a place that schooled him in the jazz, R&B, rock and roll, jump blues, funk and Mardi Gras Indian sounds that would come to shape his music.
It added: "The family thanks all whom shared his unique musical journey & requests privacy at this time". As WWOZ (90.7 FM) noted in a post this morning, you can tune in "today, and in the coming days, for much more Dr. John music on our airwaves".
"As a Rock And Roll Fall Of Fame inductee, six time Grammy victor, songwriter, composer, producer and performer, he created a unique blend of music which carried his home town, New Orleans, at its heart, as it was always in his heart".
The family of the Louisiana-born musician known as Dr. John says the celebrated singer and piano player who blended black and white musical influence with a hoodoo-infused stage persona and gravelly bayou drawl, has died.
However, he had not been seen in public since the end of 2017 after he cancelled several of his concerts.
Following news of his death, figures from the music world paid tribute.
Former Beatles drummer Ringo Starr also paid tribute, tweeting a picture of himself with Dr John along with the message: "God bless Dr. John peace and love to all his family I love the doctor peace and love".
He began performing as a teenager and was a top session musician before embarking on a solo career with his 1968 album Gris-Gris.
Dr. John scored a United States top 10 hit in 1973 with Right Time, Wrong Place. He showed the world Louisiana's rich musical heritage, and his passion for music has left a mark on the industry unlike any other.
Rest in peace, Dr. John. He went on to release over 30 albums through the decades.