The CDC and FDA are still investigating.
Pre-packaged branded pig ears have not been recalled.
While bulk pig ear products in a MI store tested positive for salmonella, no cases of salmonella-related illness are confirmed to be a result of purchasing pig ears from Pet Supplies Plus.
No one has died, but a dozen people have been hospitalized, according to the agency.
"It is not recommended to allow Pets to lick your face, it is also important to clean the items in the house that could come into contact with contaminated pig ears or forage for animals", recommended CDC.
Forty-five people across California, Illinois, Indiana, Iowa, Kansas, Massachusetts, Michigan, Missouri, New York, North Dakota, Pennsylvania, South Carolina and Wisconsin have been infected.
Individuals appear to have gotten sick from touching the dog treats or a pet that was given the treat, the feds said.
Pets infected with salmonella may be lethargic and have fever, and vomiting, officials said, adding that some pets also may have decreased appetites and abdominal pain.
Officials say no specific supplier of the dog treats has been identified at this time.
For more information, visit the CDC's website here.
None of those cases are confirmed to be a result of buying pig ears from Pet Supplies Plus.
In humans, the CDC said the infection can cause symptoms like "diarrhea, fever and abdominal cramps 12 to 72 hours after infection". The CDC says dogs don't always show that they're not feeling well with a salmonella infection, but they usually have diarrhea and may have blood or mucus in their stool.
Owners should wash their hands with soap and water after handling pet food or treats, including pig ears.