Fast and furious Serena Williams dropped just one game as she blew away China's Wang Qiang 6-1 6-0.
The 27-year-old Wang had not lost a set during her best Slam run that included a defeat of reigning French Open champion Ashleigh Barty in the last 16, but she was powerless to stop a Williams onslaught at Arthur Ashe Stadium.
Looking as dominant as can be as she moved closer to a 24th Grand Slam singles trophy and seventh U.S. Open championship, Williams was not troubled one bit by the right ankle she rolled in her previous match. Williams won 90% of her first serve points, won all five of her break point chances and had 25 winners to 10 unforced errors.
"I never thought that I would get to 100", Williams said on court after the match on Tuesday. "She's one of those players that does everything really well, so I have to do everything well too", Williams said.
Nadal, who has won three of his 18 major titles at Flushing Meadows, is playing in his 40th career Grand Slam quarterfinal.
"It feels like, you know, hard work pays off when that happens", Women's Tennis Association (WTA) quoted Williams as saying.In the semi-finals, Williams will compete against Elina Svitolina of Ukraine on September 6. "She made the semis at Wimbledon and I feel she wants to go one step further, so I feel I'll have to come out and play really well". She remains winless against the World No. 5.
"I think I'm generally stronger", Svitolina said. "She remembers everything. She will definitely remember".
Nadal reeled off nine games in succession across the third and fourth sets and 12 of the final 15 to nail down a 40th Grand Slam quarter-final appearance, nine of which have come at the US Open.
"She doesn't make a lot of mistakes", said Williams when asked about the upcoming matchup.
Svitolina had already knocked out two-time former champion Venus Williams and 2017 runner-up Madison Keys and is in a class of her own as the only Ukrainian woman to reach this stage at a major.
"I'm very happy with how I handled the pressure".
Williams' performance had the viewing audience in awe, with well-known ESPN pundit Mike Golic Jnr summing up the sentiment with a simple tweet: "Serena snatching souls tonight".
"She is obviously a fighter", Serena said. "I was surprised, too".
"She gets a lot of balls back. Still, I was quite consistent, I would say, but I had some tough matches round of 16, quarterfinals before I started to win them".
The couple is the first to simultaneously reach the quarterfinals of the US Open in at least a decade.