While they kept a clean sheet in their opening 3-0 Europa League Group F win over Eintracht Frankfurt last month, they have conceded 11 goals in seven Premier League games this season, more than any other side in the top six.
Young English player Smith-Rowe is being monitored after his head injury during the Carabao Cup game at home to Nottingham Forest last week.
Héctor Bellerín and Kieran Tierney are set to feature for Arsenal in the Europa League clash with Standard Liège on Thursday.
Upfront, Pierre-Emerick Aubameyang will certainly get a breather after his recent excursions in the league.
The Mesut Ozil era is all over bar the shouting - it seems just a question of when Arsenal manage to move him on - but he should also start after his omission from the matchday squad for Monday's trip to Old Trafford.
However, with Hearts players Steven Naismith and John Souttar both recovering from injury, no-one from the Capital is included for the European Championship qualifiers against Russian Federation and San Marino later this month.
Emery revealed he had not spoken to Clarke, but added: "I asked Kieran yesterday, because we were waiting for him to be consistently playing with [Arsenal]". Tomorrow is a good opportunity, he is ready to play.
"He played with the under-23s for taking confidence and he was doing actions on the pitch to feel good and to repeat them when the level is higher", Emery continued. "For tomorrow, we are thinking that it depends on the training that we are going to do now, on how he is feeling".