England worldwide Oxlade-Chamberlain s victor comes after his brace at Genk and an impressive performance on Tuesday as Klopp started with Roberto Firmino and Sadio Mane on the bench ahead of the weekend s huge clash with Premier League title rivals Manchester City.
On Tuesday, things started brightly for Liverpool, there was a commitment to getting the ball out wide to full-backs James Milner and Trent Alexander-Arnold and a low corner was nearly converted by Virgil Van Djik, but his shot was scooped over the bar.
Jurgen Klopp has discussed Liverpool's lack of clean sheets but insists he remains unconcerned by their defensive vulnerability in recent fixtures.
A tactic that, usually, would play into the hands of Liverpool, but on the night didn't prove fruitful.
The England worldwide soldiered on and played a further 40 minutes, during which he scored the winning goal of the game.
Genk, however, had only a handful of chances throughout the game but scored with their first shot on target in the 40th minute.
Genk, who remain without a win in the group stage and are bottom with one point, can take some heart from a performance which caused Klopp's side plenty of frustration at an unusually quiet Anfield. A goal for either team before half-time would swing the game.
Jurgen Klopp and his opposite number Felice Mazzu came out for the second half unchanged from the first spell.
The game's biggest moment was decided by its best player.
"It was a good goal from them".
More of the same will be required from the fringe players over the coming months.
Genk pushed for the equaliser in the final few minutes of the match, but the sixth time European champions ran out victors in the end.
"The most important thing; we won and nobody is injured".
Napoli drew at home to Red Bull Salzburg to hand the advantage in the group to Liverpool.