KOKO London, a music venue in the city's Camden Town district, caught fire on Monday night.
The fire at KOKO in Camden Town is under control and is now being delayed.
London Fire Brigade (LFB) said crews were working hard to save the rest of the building near Mornington Crescent station.
The roof of the building, located on London's Camden High Street, was engulfed in flame last night, with videos of the blaze being posted on social media.
As the blaze was called in, 60 firefighters from six brigades rushed to the scene, where they are now making a desperate effort to save the nightclub, once named The Music Machine and Camden Palace.
According to BBC News, KOKO owner Olly Bengough was "deeply saddened" by the fire, telling the outlet, "We'll be doing our best to get the redevelopment of this iconic building back on track". Awesome response from our firefighters.
He told this newspaper: "It did look like it took off very quickly, but I'm just relieved it was brought under control so quickly".
The venue, which first opened in 1900, had been closed for refurbishment since March 2019, and was set to re-open in March 2020. Koko should reopen in spring 2020.
The cause of the fire is not yet known.
Fire crews will remain at the scene throughout the day.